Toxicology MSDT
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Glossary
Knowledge Check Solutions

1)
High water solubility and small particle size - This is the correct answer.
In contrast to absorption via the gastrointestinal tract or through the skin, gases and particles, which are water-soluble (and thus blood soluble), will be absorbed more efficiently from the lung alveoli. Very small particles (<1 μM) are able to penetrate deep into the alveolar sacs where they can deposit and be absorbed.

2) Tracheobronchial region - This is the correct answer.
Particles 2-5 µM can penetrate into the tracheobronchial region. Very small particles (<1 μM) are able to penetrate deep into the alveolar sacs where they can deposit and be absorbed.
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